What's the Alt+F4 Equivalent on a Mac?

Quick answer: Use ⌘Q to quit an app (the true Alt+F4 equivalent) and ⌘W to close just the current window or workbook. On a Mac an app can keep running with no windows open, so the two are not interchangeable. If an app is frozen, press ⌥⌘Esc for Force Quit.
Why a Mac needs two shortcuts where Windows needs one
On Windows, closing the last window usually quits the program. On a Mac, applications and windows are separate: closing every window with ⌘W often leaves the app running, with its menu bar still at the top of the screen. ⌘Q is what actually quits it.
| Windows | Mac | What happens |
|---|---|---|
| Alt+F4 | ⌘Q | Quits the whole application |
| Ctrl+F4 / Ctrl+W | ⌘W | Closes the front window or document |
| Ctrl+Alt+Delete → Task Manager | ⌥⌘Esc | Opens Force Quit Applications |
| Win+D | ⌘H or F11 | Hide app / show desktop |
Which one you want
Done with the document, not the app? Press ⌘W. In Excel this closes the workbook and prompts to save.
Done with the app entirely? Press ⌘Q. In Excel this closes every workbook and quits.
App not responding? Press ⌥⌘Esc, select the app, click Force Quit. You can also hold ⌥ and right-click the Dock icon, then choose Force Quit.
Excel-specific notes
Excel for Mac keeps running after the last workbook closes, showing only the gallery or a blank state. That is normal. ⌘Q fully quits it. If unsaved changes exist, Excel prompts before quitting. For the rest of the window and file shortcuts, see the Complete Mac Excel shortcut cheat sheet.
Common mistakes
Pressing ⌘W expecting the app to quit. It usually will not — check the menu bar to see what app still has focus.
Holding ⌥ and pressing F4. On a Mac F4 opens Spotlight or Launchpad on many keyboards; it is not a close shortcut.
Force quitting when a save prompt is waiting. Force Quit discards unsaved work. Try ⌘Q first and answer the prompt.
FAQs
Is there a single key like F4 that closes a Mac window?
No. The Mac convention is ⌘W for windows and ⌘Q for apps. You can add a custom shortcut in System Settings, but the modifier-based ones are standard everywhere.
What is Ctrl+Alt+Delete on a Mac?
Press ⌥⌘Esc to open Force Quit Applications — the closest equivalent for dealing with a stuck app.
Does ⌘Q save my work?
It prompts you. Most apps, Excel included, ask to save unsaved changes before quitting.